Motif ID | Motif Logo | Scanned Score Distribution | Frequency of Motif | Replicability Score | Evolutionary Conservation Score | Gene Targets | Gene Ontology of CpGMM targets |
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CG_hsf1_promoter_n_PM_12_36_3 | ![]() |
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3 | 0.5 | 1.22E-04 | PAM16, GAMT, PGAM2, CHCHD4, CALY | protein import into mitochondrial intermembrane space [BP], clathrin light chain binding [MF], guanidinoacetate N-methyltransferase activity [MF], 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [MF], protein targeting to mitochondrion [BP] |
CG_hsf1_promoter_n_PM_12_31_2 | ![]() |
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2 | 0.5 | 1.07E-04 | SFRP5, DNASE2 | deoxyribonuclease II activity [MF], negative regulation of Wnt receptor signaling pathway involved in digestive tract morphogenesis [BP] |
CG_hsf1_promoter_n_PM_14_13_2 | ![]() |
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1 | 0.25 | 4.19E-05 | AGA, NAMPT, TPT1 | negative regulation of ectoderm development [BP], N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity [MF], nicotinamide phosphoribosyltransferase activity [MF] |
CG_hsf1_promoter_n_PM_12_28_3 | ![]() |
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2 | 0.25 | 1.67E-04 | TBXA2R, SLC27A5 | thromboxane A2 receptor activity [MF], cholate-CoA ligase activity [MF] |
CG_hsf1_promoter_n_PM_12_30_2 | ![]() |
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2 | 0.5 | 6.47E-05 | ANKLE2, UROC1, AXIN1, TAX1BP3 | urocanate hydratase activity [MF], beta-catenin binding [MF], mitotic nuclear envelope reassembly [BP] |
CG_hsf1_promoter_n_PM_14_6_1 | ![]() |
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1 | 0.25 | 5.79E-05 | GOT2 | glutamate catabolic process to 2-oxoglutarate [BP], L-aspartate:2-oxoglutarate aminotransferase activity [MF], glutamate catabolic process to aspartate [BP], aspartate biosynthetic process [BP] |
CG_hsf1_promoter_n_PM_12_8_1 | ![]() |
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5 | 0.75 | 1.92E-05 | TAP2, NTAN1 | peptide antigen transport [BP], tapasin binding [MF], protein-N-terminal asparagine amidohydrolase activity [MF], antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [BP], positive regulation of antigen processing and presentation of peptide antigen via MHC class I [BP], cytosol to ER transport [BP], antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [BP], TAP complex [CC], antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [BP], TAP2 binding [MF], TAP1 binding [MF], peptide antigen-transporting ATPase activity [MF], oligopeptide-transporting ATPase activity [MF] |
CG_hsf1_promoter_n_PM_14_11_3 | ![]() |
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1 | 0.25 | 9.96E-05 | TFRC, UROC1, L1CAM, CHRNA4 | urocanate hydratase activity [MF], external side of plasma membrane [CC], transferrin receptor activity [MF] |
CG_hsf1_promoter_n_PM_12_25_3 | ![]() |
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2 | 0.5 | 6.07E-05 | ST6GALNAC4, PLD6 | P granule organization [BP], (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity [MF], cardiolipin hydrolase activity [MF] |
CG_hsf1_promoter_n_PM_14_8_1 | ![]() |
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1 | 0.25 | 8.66E-06 | POLR2E | DNA-directed RNA polymerase II, core complex [CC] |
CG_hsf1_promoter_n_PM_14_1_2 | ![]() |
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2 | 0.5 | 5.27E-05 | NXN, EPHA2, CSF3R, MUC4, LAMB1 | notochord cell development [BP], protein-disulfide reductase activity [MF], extracellular matrix structural constituent [MF], cell adhesion [BP], laminin-2 complex [CC], laminin-8 complex [CC] |
CG_hsf1_promoter_n_PM_12_37_5 | ![]() |
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3 | 0.5 | 1.89E-05 | HTR2B, UROC1 | cellular response to temperature stimulus [BP], urocanate hydratase activity [MF] |
CG_hsf1_promoter_n_PM_14_4_1 | ![]() |
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1 | 0.25 | 4.48E-05 | GPC3, IL1B | positive regulation of myosin light chain kinase activity [BP], glycosaminoglycan metabolic process [BP], smooth muscle adaptation [BP], mesenchymal cell proliferation involved in ureteric bud development [BP], negative regulation of adiponectin secretion [BP], positive regulation of calcidiol 1-monooxygenase activity [BP], positive regulation of heterotypic cell-cell adhesion [BP], glycosaminoglycan biosynthetic process [BP], positive regulation of cell adhesion molecule production [BP], peptidyl-dipeptidase inhibitor activity [MF], positive regulation of monocyte chemotactic protein-1 production [BP], monocyte aggregation [BP] |
CG_hsf1_promoter_n_PM_12_27_2 | ![]() |
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2 | 0.25 | 1.66E-04 | POFUT2, MAPK12, SHH | negative regulation of kidney smooth muscle cell differentiation [BP], peptide-O-fucosyltransferase activity [MF], myoblast differentiation [BP], mesenchymal smoothened signaling pathway involved in prostate gland development [BP], positive regulation of skeletal muscle cell proliferation [BP], regulation of mesenchymal cell proliferation involved in prostate gland development [BP], positive regulation of muscle cell differentiation [BP], multicellular structure septum development [BP], negative regulation of ureter smooth muscle cell differentiation [BP], positive regulation of ureter smooth muscle cell differentiation [BP], positive regulation of sclerotome development [BP], positive regulation of kidney smooth muscle cell differentiation [BP] |
CG_hsf1_promoter_n_PM_12_22_3 | ![]() |
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1 | 0.25 | 1.65E-05 | SLC24A6 | mitochondrial calcium ion transport [BP], calcium:sodium antiporter activity [MF] |
CG_hsf1_promoter_n_PM_12_5_2 | ![]() |
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1 | 0.25 | 2.45E-05 | PECR | phytol metabolic process [BP] |
CG_hsf1_promoter_n_PM_14_17_2 | ![]() |
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3 | 0.75 | 6.04E-05 | SFRP2 | negative regulation of dermatome development [BP], metalloenzyme activator activity [MF] |
CG_hsf1_promoter_n_PM_12_24_2 | ![]() |
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3 | 0.75 | 2.30E-04 | TRAF6, ATP2A3, ERCC2, HCFC1, IL4I1, TFAP4 | L-amino-acid oxidase activity [MF], positive regulation of DNA binding [BP], nuclear membrane [CC], histone deacetylase binding [MF], protein complex assembly [BP], positive regulation of viral transcription [BP], positive regulation of gene expression [BP] |
CG_hsf1_promoter_n_PM_12_18_2 | ![]() |
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2 | 0.5 | 6.85E-05 | CYBA, SNX8, SULT2A1, IL2RA | smooth muscle hypertrophy [BP], regulation of T cell homeostatic proliferation [BP], early endosome to Golgi transport [BP], bile-salt sulfotransferase activity [MF], negative regulation of glomerular filtration by angiotensin [BP] |
CG_hsf1_promoter_n_PM_12_33_3 | ![]() |
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2 | 0.5 | 2.24E-04 | CRYL1, UROC1, DPYS | urocanate hydratase activity [MF], L-gulonate 3-dehydrogenase activity [MF], thymine binding [MF], uracil binding [MF] |
CG_hsf1_promoter_n_PM_14_7_2 | ![]() |
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2 | 0.5 | 2.00E-05 | ACOX2 | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity [MF] |
CG_hsf1_promoter_n_PM_12_29_4 | ![]() |
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3 | 0.75 | 3.94E-05 | AQP7 | urea channel activity [MF] |
CG_hsf1_promoter_n_PM_12_4_4 | ![]() |
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1 | 0.25 | 2.28E-04 | MYBBP1A, PEX1 | NLS-dependent protein nuclear import complex [CC], microtubule-based peroxisome localization [BP] |
CG_hsf1_promoter_n_PM_12_21_1 | ![]() |
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1 | 0.25 | 1.26E-05 | JAG2 | gamma-delta T cell differentiation [BP], auditory receptor cell fate commitment [BP], Notch binding [MF] |
CG_hsf1_promoter_n_PM_14_9_1 | ![]() |
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3 | 0.75 | NAN | SPARC | response to L-ascorbic acid [BP] |
CG_hsf1_promoter_n_PM_12_32_2 | ![]() |
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3 | 0.75 | 6.04E-05 | FLNA | Myb complex [CC] |
CG_hsf1_promoter_n_PM_14_14_2 | ![]() |
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3 | 0.75 | 1.10E-04 | TGDS | dTDP-glucose 4,6-dehydratase activity [MF] |
CG_hsf1_promoter_n_PM_14_18_1 | ![]() |
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2 | 0.5 | 8.80E-05 | SCN11A, NUP153 | C-fiber [CC], viral penetration into host nucleus [BP], negative regulation of RNA export from nucleus [BP], nuclear pore nuclear basket [CC] |
CG_hsf1_promoter_n_PM_14_12_4 | ![]() |
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2 | 0.5 | 1.39E-05 | CAMTA2 | cardiac muscle hypertrophy in response to stress [BP] |
CG_hsf1_promoter_n_PM_12_1_7 | ![]() |
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3 | 0.75 | 4.05E-05 | WNT7B, SGSH | establishment or maintenance of polarity of embryonic epithelium [BP], N-sulfoglucosamine sulfohydrolase activity [MF], outer medullary collecting duct development [BP] |
CG_hsf1_promoter_n_PM_16_4_1 | ![]() |
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1 | 0.25 | 1.01E-05 | POLR2L | regulation of transcription from RNA polymerase I promoter [BP], DNA-directed RNA polymerase II, core complex [CC] |
CG_hsf1_promoter_n_PM_12_2_3 | ![]() |
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3 | 0.75 | 3.07E-05 | DACT2, MYLK | negative regulation of nodal signaling pathway [BP], aorta smooth muscle tissue morphogenesis [BP], inner medullary collecting duct development [BP] |
CG_hsf1_promoter_n_PM_12_6_3 | ![]() |
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2 | 0.5 | 7.16E-05 | FOXA2, LGR4, C1QL1 | ectoderm formation [BP], regulation of transcription from RNA polymerase II promoter involved in detection of glucose [BP], negative regulation of detection of glucose [BP], locomotory behavior [BP], negative regulation of glucokinase activity [BP], negative regulation of transcription from RNA polymerase II promoter by glucose [BP], canonical Wnt receptor signaling pathway involved in metanephric kidney development [BP], central nervous system myelin formation [BP], positive regulation of transcription from RNA polymerase II promoter by glucose [BP] |
CG_hsf1_promoter_n_PM_12_14_3 | ![]() |
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1 | 0.25 | 4.86E-05 | SLC25A29, IP6K3, LIPE | hormone-sensitive lipase activity [MF], inositol hexakisphosphate 6-kinase activity [MF], acyl carnitine transmembrane transporter activity [MF] |
CG_hsf1_promoter_n_PM_12_10_2 | ![]() |
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1 | 0.25 | 8.13E-06 | CYP2D6, SLC6A12, CYP11B2 | electron carrier activity [MF], corticosterone 18-monooxygenase activity [MF], monooxygenase activity [MF], regulation of blood volume by renal aldosterone [BP], steroid 11-beta-monooxygenase activity [MF], negative regulation of cellular organofluorine metabolic process [BP], cellular water homeostasis [BP], heme binding [MF], iron ion binding [MF] |
CG_hsf1_promoter_n_PM_16_8_2 | ![]() |
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1 | 0.25 | 3.52E-05 | MRPL36 | mitochondrial large ribosomal subunit [CC] |
CG_hsf1_promoter_n_PM_12_7_2 | ![]() |
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2 | 0.5 | 1.78E-04 | ALDH7A1 | betaine-aldehyde dehydrogenase activity [MF], L-aminoadipate-semialdehyde dehydrogenase activity [MF] |
CG_hsf1_promoter_n_PM_16_5_2 | ![]() |
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2 | 0.5 | 4.88E-05 | NT5C2 | nucleoside phosphotransferase activity [MF] |
CG_hsf1_promoter_n_PM_12_12_2 | ![]() |
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1 | 0.25 | 1.24E-04 | ALG12 | dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity [MF], alpha-1,6-mannosyltransferase activity [MF] |
CG_hsf1_promoter_n_PM_12_35_2 | ![]() |
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3 | 0.75 | 1.34E-04 | COLEC12, AXIN1, HRAS | canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation [BP], axial mesoderm formation [BP], Wnt receptor signaling pathway involved in forebrain neuron fate commitment [BP], carbohydrate mediated signaling [BP], positive regulation of MAP kinase activity [BP], olfactory placode formation [BP], positive regulation of miRNA metabolic process [BP], positive regulation of ruffle assembly [BP], positive regulation of JNK cascade [BP], positive regulation of GTPase activity [BP], protein C-terminus binding [MF], optic placode formation [BP] |
CG_hsf1_promoter_n_PM_14_2_1 | ![]() |
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1 | 0.25 | 1.56E-04 | MYBBP1A | NLS-dependent protein nuclear import complex [CC] |
CG_hsf1_promoter_n_PM_12_26_3 | ![]() |
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1 | 0.25 | 1.35E-04 | LAMA5, FASN | 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity [MF], 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [MF], enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity [MF], [acyl-carrier-protein] S-acetyltransferase activity [MF], endothelial cell differentiation [BP], 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [MF] |
CG_hsf1_promoter_n_PM_12_15_2 | ![]() |
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1 | 0.25 | 3.88E-05 | PCYT2, SLC25A1 | mitochondrial citrate transport [BP], ethanolamine-phosphate cytidylyltransferase activity [MF] |
CG_hsf1_promoter_n_PM_16_3_2 | ![]() |
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1 | 0.25 | 1.90E-05 | WARS2, TRPC4, AXIN1, NPTN | canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation [BP], Wnt receptor signaling pathway involved in forebrain neuron fate commitment [BP], tryptophanyl-tRNA aminoacylation [BP], cell adhesion molecule binding [MF], beta-catenin binding [MF], tryptophan-tRNA ligase activity [MF] |
CG_hsf1_promoter_n_PM_16_2_8 | ![]() |
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4 | 0.75 | 4.43E-05 | NTAN1 | protein-N-terminal asparagine amidohydrolase activity [MF] |